Glu298Asp polymorphism influences the beneficial effects of fish oil fatty acids on postprandial vascular function
نویسندگان
چکیده
منابع مشابه
DHA-rich fish oil reverses the detrimental effects of saturated fatty acids on postprandial vascular reactivity.
BACKGROUND Experimental elevation of nonesterified fatty acids (NEFAs) impairs endothelial function, but the effect of NEFA composition is unknown. OBJECTIVE The objective was to test the effect of acute elevation of NEFAs enriched with either saturated fatty acids (SFAs) or SFAs with long-chain (LC) n-3 (omega-3) PUFAs on vascular function measured via flow-mediated dilatation (FMD), laser D...
متن کاملFish oil fatty acids improve postprandial vascular reactivity in healthy men.
Chronic fish oil intervention had been shown to have a positive impact on endothelial function. Although high-fat meals have often been associated with a loss of postprandial vascular reactivity, studies examining the effects of fish oil fatty acids on vascular function in the postprandial phase are limited. The aim of the present study was to examine the impact of the addition of fish oil fatt...
متن کاملFish Oil Fatty Acids Improve Post-meal Vascular Reactivity
In the present study, the authors measured vascular functioning of the forearm of 25 male subjects via ultrasound (Doppler imaging) at time zero and after 4 hours after consuming a high-fat meal. Using a single-blinded crossover design, the subjects either consumed a placebo oil (no DHA/EPA present) or fish oil (providing a total amount of DHA/EPA amounting to 5.4 grams-3.24 grams DHA plus 2.16...
متن کاملIncorporated Fish Oil Fatty Acids Prevent Action Potential Shortening Induced by Circulating Fish Oil Fatty Acids
Increased consumption of fatty fish, rich in omega-3-polyunsaturated fatty acids (ω3-PUFAs) reduces the severity and number of arrhythmias. Long-term ω3-PUFA-intake modulates the activity of several cardiac ion channels leading to cardiac action potential shortening. Circulating ω3-PUFAs in the bloodstream and incorporated ω3-PUFAs in the cardiac membrane have a different mechanism to shorten t...
متن کاملFish oil and omega-3 fatty acids.
What are Omega-3 Fatty Acids and Why are They Helpful? Omega-3 fatty acids have become quite popular because of the many positive effects on human health. Omega-3 fatty acids benefit both healthy people as well as those with cardiovascular disease. Omega-3 fatty acids are thought to improve heart health by lowering triglycerides, raising good cholesterol (HDL, or high density lipoprotein), thin...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 2012
ISSN: 0022-2275
DOI: 10.1194/jlr.p025080